Istanbul, the most populous city in Turkey and its de-facto economic, cultural and historical centre. Historically, its location was of great strategic importance. It nests directly on the silk road and is the only sea route between the black sea and the Mediterranean. Today, it is the only country that is both in continental Europe and Asia.
Obviously, 48 hours does not do justice to Istanbul’s extremely unique and historically rich culture. But nonetheless, for those short on time, this will do.